Sodium carboxyl methylstarch（SSG） CAS NO.9063-38-1

Sodium carboxymethyl starch

The starch derivatives of this strain are mainly used as disintegrators in solid preparations. It has good water absorption and expansion, while accelerating the disintegration of the tablet with compressibility, can improve the formability of the tablet, increase the hardness of the tablet without affecting its disintegration, the dosage is 0.5-8%, the usual dosage is 3%. The method of use is generally external or external addition. It also has more powerful swelling properties, which can accelerate the disintegration of tablets, thereby improving the dissolution and bioavailability of drugs. Generally, the usual dosage is 2-8%, which can be used for external or internal and external addition.

Product key information
Implementation standards: China Pharmacopoeia 2020 edition; USP; GB 29937-2013
Functional use: solid preparation disintegrator, filler
Product category: Finished products | starch
Product properties: white or white powder; No odor; It is hygroscopic in air. This product rapidly absorbs water and expands to form a viscous colloidal solution, which is insoluble in methanol, ethanol or ether.
CAS number: 9063-38-1
Packing specification: 25kg/ barrel; 25kg/ bag
Material label: Pharmaceutical excipients Food additives

Feature recommendation
◆ As a capsule and tablet disintegrant is widely used in oral preparations, good compressibility

◆ Suitable for dry direct pressing and wet granulating

◆ Fast water absorption, significant swelling

◆ Less affected by hydrophobic excipients

◆ Can withstand greater tablet pressure without affecting disintegration

◆ Look forward to higher performance of "fast collapse King"

◆ Low viscosity can also be used as a binder for tablets

◢ Sodium carboxymethyl starch through rapid water absorption, to achieve rapid and significant swelling, so as to play the role of disintegration.

◢ Suitable for direct pressing or wet granulation process. The range commonly used in formulations is 2 to 8%.

◢ Although the disintegration of many disintegrants is affected by hydrophobic excipients (such as lubricants), sodium carboxymethyl starch is less affected by it. Increasing tablet pressure also appeared to have no effect on disintegration time.

◢ Sodium carboxymethyl starch has also been studied as a suspension aid.

Ionic ether disintegrating agent, mainly used for disintegrating solid preparations
◎ It has good water absorption and expansion, and it is also compressible

◎ Can improve the formability of the tablet, increase the hardness of the tablet without affecting its disintegration

◎ Can accelerate the disintegration of tablets, greatly improve the dissolution and bioavailability of drugs

◎ Sodium carboxymethyl starch with relatively high viscosity can be used as a slow-release material

◎ Used for psychotropic drugs, antipyretic analgesics, digestive system drugs

Special use of product
◎ Tablets prepared with sodium carboxymethyl starch have good storage properties. Although sodium carboxymethyl starch has a very strong hygroscopic property, it has good stability. Should be stored in a closed container, so as not to be affected by humidity, temperature changes, resulting in caking.

◎ Stored at the appropriate temperature and humidity, its physical properties can be maintained for up to 3 years.

◎ Incompatibility with ascorbic acid and aminoglycoside antibiotics.

Package&Shipping

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