Industrial Pharma Grade N-Vinyl-2-pyrrolidone (NVP) CAS NO.88-12-0
- FOB Price: USD: /Metric Ton Get Latest Price
- Min.Order: 1 Metric Ton
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Available Specifications:
99.5(1-10)Metric Ton
- Product Details
Keywords
- 2-Pyrrolidinone,1-vinyl- (7CI,8CI)
- 1-Ethenyl-2-pyrrolidinone
- 1-Vinyl-2-pyrrolidinone
Quick Details
- ProName: Liquid N-Vinyl-2-pyrrolidone
- CasNo: 88-12-0
- Molecular Formula: C6H9NO
- Appearance: Colorless to yellow liquid
- Application: Adhesives, textiles, UV coatings, phar...
- DeliveryTime: 3-5days
- PackAge: 200L Drum
- Port: Any port in China
- ProductionCapacity: 100000 Metric Ton/Month
- Purity: 99.5
- Storage: Dry cool and clean warehouse
- Transportation: By sea or air
- LimitNum: 1 Metric Ton
- Operating Temperature: 13-14 °C
Superiority
SAFETY DATA SHEETS
According to the UN GHS revision 10
Version: 1.0
Creation Date: July 15, 2019
Revision Date: July 15, 2019
SECTION 1: Identification
1.1GHS Product identifier
Product name |
1-vinyl-2-pyrrolidone |
---|
1.2Other means of identification
Product number |
- |
---|---|
Other names |
2-Pyrrolidinone, 1-ethenyl-; N-Vinyl-2-pyrrolidone |
1.3Recommended use of the chemical and restrictions on use
Identified uses |
Industrial and scientific research use. |
---|---|
Uses advised against |
no data available |
SECTION 2: Hazard identification
2.1Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Acute toxicity - Category 4, Dermal
Serious eye damage, Category 1
Acute toxicity - Category 4, Inhalation
Specific target organ toxicity – single exposure, Category 3
Carcinogenicity, Category 2
Specific target organ toxicity – repeated exposure, Category 2
2.2GHS label elements, including precautionary statements
Pictogram(s) | |
---|---|
Signal word |
Danger |
Hazard statement(s) |
H302 Harmful if swallowed H312 Harmful in contact with skin H318 Causes serious eye damage H332 Harmful if inhaled H335 May cause respiratory irritation H351 Suspected of causing cancer H373 May cause damage to organs through prolonged or repeated exposure |
Precautionary statement(s) | |
Prevention |
P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P203 Obtain, read and follow all safety instructions before use. P260 Do not breathe dust/fume/gas/mist/vapours/spray. |
Response |
P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P317 Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell. P318 IF exposed or concerned, get medical advice. |
Storage |
P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. |
Disposal |
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. |
2.3Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
3.1Substances
Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
---|---|---|---|---|
1-vinyl-2-pyrrolidone | 1-vinyl-2-pyrrolidone | 88-12-0 | 201-800-4 | 100% |
SECTION 4: First-aid measures
4.1Description of necessary first-aid measures
If inhaled
Fresh air, rest. Refer for medical attention.
Following skin contact
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Following eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Following ingestion
Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .
4.2Most important symptoms/effects, acute and delayed
SYMPTOMS: This compound may cause interstitial fibrosis in the lungs. Lesions regress when patient is no longer being exposed to the compound. (NTP, 1992)
4.3Indication of immediate medical attention and special treatment needed, if necessary
Minimum/Potential Fatal Human Dose
1. 1= practically nontoxic: probable oral lethal dose (human) above 15 g/kg, more than 1 quart (2.2 lb) for 70 kg person (150 lb).
Absorption, Distribution and Excretion
When given parenterally, unexcreted particles are phagocytized by cells of reticuloendothelial system & deposited in storage sites in liver, spleen, lung, bone marrow...
SECTION 5: Fire-fighting measures
5.1Suitable extinguishing media
Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
5.2Specific hazards arising from the chemical
Flash point data for this chemical are not available, but it is probably non-flammable. (NTP, 1992)
5.3Special protective actions for fire-fighters
Use water spray, powder, foam, carbon dioxide.
SECTION 6: Accidental release measures
6.1Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
6.2Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
6.3Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
7.1Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
7.2Conditions for safe storage, including any incompatibilities
Separated from strong acids. Keep in the dark. Cool. Store only if stabilized.
SECTION 8: Exposure controls/personal protection
8.1Control parameters
Occupational Exposure limit values
TLV: 0.05 ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans).MAK: 0.047 mg/m3, 0.01 ppm; peak limitation category: II(2); skin absorption (H); carcinogen category: 4; pregnancy risk group: C
Biological limit values
no data available
8.2Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
8.3Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Wear safety goggles or eye protection in combination with breathing protection.
Skin protection
Protective gloves.
Respiratory protection
Use ventilation, local exhaust or breathing protection.
Thermal hazards
no data available
SECTION 9: Physical and chemical properties and safety characteristics
Physical state |
Liquid. |
---|---|
Colour |
Colourless. |
Odour |
ODORLESS |
Melting point/freezing point |
13 - 14 °C. Atm. press.:101.3 kPa. Remarks:No specific information on atmospheric pressure reported. Assumed to be standard pressure (101.3 kPa). |
Boiling point or initial boiling point and boiling range |
218 °C. Atm. press.:1 013 hPa.;191.2 °C. Atm. press.:500 hPa. Remarks:Based on measured vapor pressure graph. |
Flammability |
Combustible. |
Lower and upper explosion limit/flammability limit |
no data available |
Flash point |
95 °C. Atm. press.:1 013 hPa. |
Auto-ignition temperature |
240 °C. Atm. press.:101.3 kPa. Remarks:No specific information on atmospheric pressure reported. Assumed to be standard pressure (101.3 kPa). |
Decomposition temperature |
no data available |
pH |
Between 3,0 and 7,0 (5 % solution) |
Kinematic viscosity |
dynamic viscosity (in mPa s) = 2.1. Temperature:20°C.;dynamic viscosity (in mPa s) = 1.7. Temperature:50.0°C. |
Solubility |
greater than or equal to 100 mg/mL at 68° F (NTP, 1992) |
Partition coefficient n-octanol/water |
log Pow = 0.4. Temperature:25 °C. Remarks:PH value is assumed. |
Vapour pressure |
0.12 hPa. Temperature:20 °C.;1.23 hPa. Temperature:50 °C. |
Density and/or relative density |
1.04 g/cm³. Temperature:20 °C. |
Relative vapour density |
3.8 (vs air) |
Particle characteristics |
no data available |
SECTION 10: Stability and reactivity
10.1Reactivity
The substance may polymerize in the presence of air due to warming, under the influence of light and acids. Decomposes on burning. This produces toxic and corrosive gases of nitrogen oxides.
10.2Chemical stability
no data available
10.3Possibility of hazardous reactions
Compatible with wide range of hydrophilic and hydrophobic resins.POLYVINYLPYRROLIDONE is a polymeric material and probably has low reactivity. It reacts as a weak base.
10.4Conditions to avoid
no data available
10.5Incompatible materials
no data available
10.6Hazardous decomposition products
When heated to decomposition it emits toxic fumes of nitroxides. Poly(1-vinyl-2-pyrrolidinone) homopolymer and Hueper's polymer 1-7
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male/female) - 1 043 mg/kg bw. Remarks:Original data: LD50 = 1.0 mL/kg bw; calculated with a density of 1.043 g/mL.
- Inhalation: LC50 - rat (male/female) - 3.07 mg/L air (analytical).
- Dermal: LD50 - rabbit - 560 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Evaluation: No epidemiological data relevant to the carcinogenicity of ... polyvinyl pyrrolidone were available. ... There is limited evidence for the carcinogenicity of polyvinyl pyrrolidone in experimental animals. Overall evaluation: ... Polyvinyl pyrrolidone is not classifiable as to its carcinogenicity in humans (Group 3).
Reproductive toxicity
no data available
STOT-single exposure
The substance is corrosive to the eyes. The substance is irritating to the respiratory tract.
STOT-repeated exposure
The substance may have effects on the liver. This may result in liver impairment. Tumours have been detected in experimental animals but may not be relevant to humans.
Aspiration hazard
A harmful contamination of the air will be reached quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
12.1Toxicity
- Toxicity to fish: LC50 - Oncorhynchus mykiss (previous name: Salmo gairdneri) - 976 mg/L - 72 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia sp. - 45 mg/L - 48 h.
- Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - > 1 000 mg/L - 72 h.
- Toxicity to microorganisms: EC90 - Pseudomonas putida - 7 150 mg/L - 17 h.
12.2Persistence and degradability
no data available
12.3Bioaccumulative potential
no data available
12.4Mobility in soil
no data available
12.5Other adverse effects
no data available
SECTION 13: Disposal considerations
13.1Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
14.1UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.) | IMDG: Not dangerous goods. (For reference only, please check.) | IATA: Not dangerous goods. (For reference only, please check.) |
14.2UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.) | IMDG: Not dangerous goods. (For reference only, please check.) | IATA: Not dangerous goods. (For reference only, please check.) |
14.3Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.) | IMDG: Not dangerous goods. (For reference only, please check.) | IATA: Not dangerous goods. (For reference only, please check.) |
14.4Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.) | IMDG: Not dangerous goods. (For reference only, please check.) | IATA: Not dangerous goods. (For reference only, please check.) |
14.5Environmental hazards
ADR/RID: No | IMDG: No | IATA: No |
14.6Special precautions for user
no data available
14.7Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
15.1Safety, health and environmental regulations specific for the product in question
Chemical name | Common names and synonyms | CAS number | EC number |
---|---|---|---|
1-vinyl-2-pyrrolidone | 1-vinyl-2-pyrrolidone | 88-12-0 | 201-800-4 |
European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
EC Inventory | Listed. | ||
United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
China Catalog of Hazardous chemicals 2015 | Not Listed. | ||
New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
Vietnam National Chemical Inventory | Listed. | ||
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
Korea Existing Chemicals List (KECL) | Listed. |
SECTION 16: Other information
Information on revision
Creation Date | July 15, 2019 |
---|---|
Revision Date | July 15, 2019 |
Package&Shipping
Details
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