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Home > Products >  Industrial Pharma Grade N-Vinyl-2-pyrrolidone (NVP)

Industrial Pharma Grade N-Vinyl-2-pyrrolidone (NVP) CAS NO.88-12-0

  • FOB Price: USD: /Metric Ton Get Latest Price
  • Min.Order: 1 Metric Ton
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    99.5(1-10)Metric Ton

  • Product Details

Keywords

  • 2-Pyrrolidinone,1-vinyl- (7CI,8CI)
  • 1-Ethenyl-2-pyrrolidinone
  • 1-Vinyl-2-pyrrolidinone

Quick Details

  • ProName: Liquid N-Vinyl-2-pyrrolidone
  • CasNo: 88-12-0
  • Molecular Formula: C6H9NO
  • Appearance: Colorless to yellow liquid
  • Application: Adhesives, textiles, UV coatings, phar...
  • DeliveryTime: 3-5days
  • PackAge: 200L Drum
  • Port: Any port in China
  • ProductionCapacity: 100000 Metric Ton/Month
  • Purity: 99.5
  • Storage: Dry cool and clean warehouse
  • Transportation: By sea or air
  • LimitNum: 1 Metric Ton
  • Operating Temperature: 13-14 °C

Superiority

SAFETY DATA SHEETS

According to the UN GHS revision 10

Version: 1.0

Creation Date: July 15, 2019

Revision Date: July 15, 2019

SECTION 1: Identification

1.1GHS Product identifier

Product name

1-vinyl-2-pyrrolidone

1.2Other means of identification

Product number

-

Other names

2-Pyrrolidinone, 1-ethenyl-; N-Vinyl-2-pyrrolidone

1.3Recommended use of the chemical and restrictions on use

Identified uses

Industrial and scientific research use.

Uses advised against

no data available

SECTION 2: Hazard identification

2.1Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Acute toxicity - Category 4, Dermal

Serious eye damage, Category 1

Acute toxicity - Category 4, Inhalation

Specific target organ toxicity – single exposure, Category 3

Carcinogenicity, Category 2

Specific target organ toxicity – repeated exposure, Category 2

2.2GHS label elements, including precautionary statements

Pictogram(s)   
Signal word

Danger

Hazard statement(s)

H302 Harmful if swallowed

H312 Harmful in contact with skin

H318 Causes serious eye damage

H332 Harmful if inhaled

H335 May cause respiratory irritation

H351 Suspected of causing cancer

H373 May cause damage to organs through prolonged or repeated exposure

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P203 Obtain, read and follow all safety instructions before use.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

Response

P301+P317 IF SWALLOWED: Get medical help.

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P317 Get medical help.

P321 Specific treatment (see ... on this label).

P362+P364 Take off contaminated clothing and wash it before reuse.

P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P319 Get medical help if you feel unwell.

P318 IF exposed or concerned, get medical advice.

Storage

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

Disposal

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

2.3Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

3.1Substances

Chemical name Common names and synonyms CAS number EC number Concentration
1-vinyl-2-pyrrolidone 1-vinyl-2-pyrrolidone 88-12-0 201-800-4 100%

SECTION 4: First-aid measures

4.1Description of necessary first-aid measures

If inhaled

Fresh air, rest. Refer for medical attention.

Following skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap.

Following eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Following ingestion

Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .

4.2Most important symptoms/effects, acute and delayed

SYMPTOMS: This compound may cause interstitial fibrosis in the lungs. Lesions regress when patient is no longer being exposed to the compound. (NTP, 1992)

4.3Indication of immediate medical attention and special treatment needed, if necessary

Minimum/Potential Fatal Human Dose

1. 1= practically nontoxic: probable oral lethal dose (human) above 15 g/kg, more than 1 quart (2.2 lb) for 70 kg person (150 lb).

Absorption, Distribution and Excretion

When given parenterally, unexcreted particles are phagocytized by cells of reticuloendothelial system & deposited in storage sites in liver, spleen, lung, bone marrow...

SECTION 5: Fire-fighting measures

5.1Suitable extinguishing media

Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

5.2Specific hazards arising from the chemical

Flash point data for this chemical are not available, but it is probably non-flammable. (NTP, 1992)

5.3Special protective actions for fire-fighters

Use water spray, powder, foam, carbon dioxide.

SECTION 6: Accidental release measures

6.1Personal precautions, protective equipment and emergency procedures

Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

6.2Environmental precautions

Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

6.3Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

SECTION 7: Handling and storage

7.1Precautions for safe handling

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

7.2Conditions for safe storage, including any incompatibilities

Separated from strong acids. Keep in the dark. Cool. Store only if stabilized.

SECTION 8: Exposure controls/personal protection

8.1Control parameters

Occupational Exposure limit values

TLV: 0.05 ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans).MAK: 0.047 mg/m3, 0.01 ppm; peak limitation category: II(2); skin absorption (H); carcinogen category: 4; pregnancy risk group: C

Biological limit values

no data available

8.2Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

8.3Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear safety goggles or eye protection in combination with breathing protection.

Skin protection

Protective gloves.

Respiratory protection

Use ventilation, local exhaust or breathing protection.

Thermal hazards

no data available

SECTION 9: Physical and chemical properties and safety characteristics

Physical state

Liquid.

Colour

Colourless.

Odour

ODORLESS

Melting point/freezing point

13 - 14 °C. Atm. press.:101.3 kPa. Remarks:No specific information on atmospheric pressure reported. Assumed to be standard pressure (101.3 kPa).

Boiling point or initial boiling point and boiling range

218 °C. Atm. press.:1 013 hPa.;191.2 °C. Atm. press.:500 hPa. Remarks:Based on measured vapor pressure graph.

Flammability

Combustible.

Lower and upper explosion limit/flammability limit

no data available

Flash point

95 °C. Atm. press.:1 013 hPa.

Auto-ignition temperature

240 °C. Atm. press.:101.3 kPa. Remarks:No specific information on atmospheric pressure reported. Assumed to be standard pressure (101.3 kPa).

Decomposition temperature

no data available

pH

Between 3,0 and 7,0 (5 % solution)

Kinematic viscosity

dynamic viscosity (in mPa s) = 2.1. Temperature:20°C.;dynamic viscosity (in mPa s) = 1.7. Temperature:50.0°C.

Solubility

greater than or equal to 100 mg/mL at 68° F (NTP, 1992)

Partition coefficient n-octanol/water

log Pow = 0.4. Temperature:25 °C. Remarks:PH value is assumed.

Vapour pressure

0.12 hPa. Temperature:20 °C.;1.23 hPa. Temperature:50 °C.

Density and/or relative density

1.04 g/cm³. Temperature:20 °C.

Relative vapour density

3.8 (vs air)

Particle characteristics

no data available

SECTION 10: Stability and reactivity

10.1Reactivity

The substance may polymerize in the presence of air due to warming, under the influence of light and acids. Decomposes on burning. This produces toxic and corrosive gases of nitrogen oxides.

10.2Chemical stability

no data available

10.3Possibility of hazardous reactions

Compatible with wide range of hydrophilic and hydrophobic resins.POLYVINYLPYRROLIDONE is a polymeric material and probably has low reactivity. It reacts as a weak base.

10.4Conditions to avoid

no data available

10.5Incompatible materials

no data available

10.6Hazardous decomposition products

When heated to decomposition it emits toxic fumes of nitroxides. Poly(1-vinyl-2-pyrrolidinone) homopolymer and Hueper's polymer 1-7

SECTION 11: Toxicological information

Acute toxicity

  • Oral: LD50 - rat (male/female) - 1 043 mg/kg bw. Remarks:Original data: LD50 = 1.0 mL/kg bw; calculated with a density of 1.043 g/mL.
  • Inhalation: LC50 - rat (male/female) - 3.07 mg/L air (analytical).
  • Dermal: LD50 - rabbit - 560 mg/kg bw.

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Evaluation: No epidemiological data relevant to the carcinogenicity of ... polyvinyl pyrrolidone were available. ... There is limited evidence for the carcinogenicity of polyvinyl pyrrolidone in experimental animals. Overall evaluation: ... Polyvinyl pyrrolidone is not classifiable as to its carcinogenicity in humans (Group 3).

Reproductive toxicity

no data available

STOT-single exposure

The substance is corrosive to the eyes. The substance is irritating to the respiratory tract.

STOT-repeated exposure

The substance may have effects on the liver. This may result in liver impairment. Tumours have been detected in experimental animals but may not be relevant to humans.

Aspiration hazard

A harmful contamination of the air will be reached quickly on evaporation of this substance at 20°C.

SECTION 12: Ecological information

12.1Toxicity

  • Toxicity to fish: LC50 - Oncorhynchus mykiss (previous name: Salmo gairdneri) - 976 mg/L - 72 h.
  • Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia sp. - 45 mg/L - 48 h.
  • Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - > 1 000 mg/L - 72 h.
  • Toxicity to microorganisms: EC90 - Pseudomonas putida - 7 150 mg/L - 17 h.

12.2Persistence and degradability

no data available

12.3Bioaccumulative potential

no data available

12.4Mobility in soil

no data available

12.5Other adverse effects

no data available

SECTION 13: Disposal considerations

13.1Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

SECTION 14: Transport information

14.1UN Number

ADR/RID: Not dangerous goods. (For reference only, please check.) IMDG: Not dangerous goods. (For reference only, please check.) IATA: Not dangerous goods. (For reference only, please check.)

14.2UN Proper Shipping Name

ADR/RID: Not dangerous goods. (For reference only, please check.) IMDG: Not dangerous goods. (For reference only, please check.) IATA: Not dangerous goods. (For reference only, please check.)

14.3Transport hazard class(es)

ADR/RID: Not dangerous goods. (For reference only, please check.) IMDG: Not dangerous goods. (For reference only, please check.) IATA: Not dangerous goods. (For reference only, please check.)

14.4Packing group, if applicable

ADR/RID: Not dangerous goods. (For reference only, please check.) IMDG: Not dangerous goods. (For reference only, please check.) IATA: Not dangerous goods. (For reference only, please check.)

14.5Environmental hazards

ADR/RID: No IMDG: No IATA: No

14.6Special precautions for user

no data available

14.7Transport in bulk according to IMO instruments

no data available

SECTION 15: Regulatory information

15.1Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
1-vinyl-2-pyrrolidone 1-vinyl-2-pyrrolidone 88-12-0 201-800-4
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Not Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.
Korea Existing Chemicals List (KECL) Listed.

SECTION 16: Other information

Information on revision

Creation Date July 15, 2019
Revision Date July 15, 2019

Package&Shipping

Details

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